By train:

Plüschow is a station on the Lübeck-Rostock line.
It takes 15 minutes to walk to the palace.

By car:

Arriving from Lübeck or Rostock: Via the A 20, take the Grevesmühlen turn off, in Upahl take the road towards Plüschow.

Arriving from Berlin: Take the motorway as far as Schwerin, drive through Schwerin then, on the B road, drive towards Grevesmühlen, in Upahl turn right towards Plüschow.